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Hi
Dr.
Ayers
I've
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Hi Dr. Ayers I've been fascinated by your work on inloimmatafn and believe that your research is helping me get closer to finding relief for my own autoimmune / reactive arthritis. I have tried using fish oil (as many as 5-7 capsules per meal) but can't understand why my arthritis (sharp, stabbing joint pain in fingers, hip, and heel) is greatly exacerbated rather than relieved. I have also tried adopting the paleo diet (mostly grass-fed lamb, raw hard cheeses, and plenty of cooked vegetables), but my immune system seems to be so hyperactive that I react within 24-36 hours of eating any food with high fat content, gluten, corn, or animal proteins. Thus far, the only foods that keep my autoimmune arthritis calm are brown rice, beans, and vegetables. I need to try reintroduce animal proteins to my body again as my current diet is unsustainable due to its low-fat and low-calorie nature (I am 5'11 and 122 lbs. as a result of this horrible starvation diet). I wonder if oral heparin might be of use in helping my body become accustomed again to animal proteins and dietary fats in general? I have read through your work on heparin and wondered what your thoughts are regarding the use of a low-dose nonanticoagulant oral heparin (or heparin analogue?) in the hope of suppressing the hyperimmune reaction and forcing the tolerance of more foods like meats, poultry, etc. My doctor is quite perplexed at this point as virtually all test results have come back normal. So, I wanted to present some ideas to him on the possible use of heparin (although I couldn't find out how much was administered in the articles I read online). Also, do you know if any side effects have been noted with the use of oral heparin? Any thoughts you have would be greatly appreciated. JeffOral heparin in the treatment of rheumatoid arthritis. Archivum immunologiae et therapiae experimentalis. Imiela, J & Nosarzewski, J & Gf3rski, A. (1995).Low-dose heparin: a novel approach in immunosuppression munomodulating activity of heparin. FASEB J 5:2287-2291. 3. Gorski A, Imiela J, Norsarzewski J. (1993) Heparan sulfate proteoglycans in glomerular inloimmatafn Kidney International (2004) 65, 768 785; doi:10.1111/j.1523-1755.2004.00451.xANGELIQUE L W M M ROPS, JOHAN VAN DER VLAG, JOOST F M LENSEN, TESSA J M WIJNHOVEN, LAMBERT P W J VAN DEN HEUVEL, TOIN H VAN KUPPEVELT and JO H M BERDENNephrology Research Laboratory and Laboratory for Matrix Biochemistry, Nijmegen Centre for Molecular Life Sciences; and Division of Nephrology and Division of Pediatrics, University Medical Centre, Nijmegen, The Netherlands
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(VISITOR) AUTHOR'S NAME Shota
MESSAGE TIMESTAMP 19 december 2014, 03:41:18
AUTHOR'S IP LOGGED 104.40.183.124
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